Adenocarcinoma of the lungs is developed in the mucosa glands of the lungs. We know of four different subpopulations – acinar, papillary, bronchioles-alveolar and solid traces which are producing the mucus. This is the most common type of lung carcinoma even with people who haven’t smoked in their lives. More than 70% of this cancer’s body is located peripherally. This is a common cell type of a cancer joined in with peripheral scars of the cancer. Usually, these cancers are firm but they can be soft and mucosa-like depending on the histopathology and presence of any scars. They grow below or into the visceral pleura, and can occasionally spread outside of pleura. Adenocarcinoma has a characteristic of forming the glands with malicious cells spread around the central lumen.
Lumens can vary in size and shape and are commonly surrounded by stromal tissue or in some cases they are infiltrated into the previously existing scar. A well differentiated tumor usually shows plentiful opening of the glands while weakly differentiated tumors show relatively more of solid tumor areas and less gland structures.
The weakest differentiated tumors are containing solid nests and blocks of malicious cells which are not classified as cancers of the large cells or weakly differentiated cancer only due to the mucosa.
Symptoms of cancer depend on the type, location and way in which it is spread. Usually, the main symptom is constant coughing. People with chronic bronchitis can notice that their coughs are becoming more intense. Blood may also appear in the coughed up matter. If the blood grows into the lower positioned blood vessels, intense bleeding can occur.
The cancer can cause rough breathing as well, around the breath channels in which it grows. Narrowing of the bronchi can lead to atelectasis, which is a condition when the bronchi dwindle. If the cancer spreads into the lungs themselves, low level of blood oxygen is probable as well as heart failure.
The cancer can also grow into some neck based nerves causing lowered eyelids, smaller pupil, and convex eye and reduced sweating on one side of the face. The summary of these symptoms is known as Homer’s syndrome. The cancer on the top of the lungs can grow into the nerves which are located in the arm, making it feel numb and week.
The cancer is also capable of growing into the esophagus or it can grow in its nearest proximity, creating pressure on it. This causes difficulties with swallowing, sometimes creating an abnormal passage through between the esophagus and the bronchi which causes severe coughs during swallowing since food and fluids are entering the lungs.
Lung cancer can spread into the blood stream, affecting liver, brain, bones and a whole list of other organs. This can happen in an early stage of the disease, especially in case of a small cell cancer. Symptoms like heart failure, cramps and pain in the bones can be developed before obvious lung problems have occurred. This makes it difficult to make an early diagnosis.
Unfortunately, lung adenocarcinoma survival rate is very poor, about 15% of a chance to survive 5 years. As sooner as the condition is uncovered, there is a higher chance of prolonging the life beyond that limit.